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Since the method can produce high and strong asperities it might also prove useful for investigations how asperities deform under sever contact conditions.<br />Access to Children and Adolescent Mental Health Services (CAMHS) can be difficult, with lengthy wait times. Many of the young people and their parents are not signposted to any form of support during their wait for initial assessment or treatment and people are increasingly turning towards web-based resources for help and advice. However, there are some concerns about the quality of the information shared online. Research on the use and quality of information shared on online platforms for mental health inquiries is limited.<br />We aimed to investigate the content and quality of the responses shared by forum users on an online forum for parents of young people with mental health needs (Mumsnet 'Talk'). Forum users were primarily parents, but 8 posts were written by posters identifying as a healthcare worker, teacher, or autism spectrum specialist.<br />Qualitative methodology was adopted for this study. Forum content from Mumsnet was extracted in an anonymised form and thematic analysis was conducted to explore ared within the extracted forum content is congruent with evidence-based knowledge. However, further investigation is needed to generate better understanding of the overall quality of mental health information available on online platforms.<br />Themes indicate that parents of children and young people with mental health needs seem to use online fora for informational support. It is promising that a significant proportion of the information shared within the extracted forum content is congruent with evidence-based knowledge. However, further investigation is needed to generate better understanding of the overall quality of mental health information available on online platforms.<br />Knowledge on Type 1 Diabetes (T1D) in sub-Saharan Africa is scarce. This study aimed at assessing microvascular complications of Type 1 diabetes in young patients.<br />A retrospective study based on medical recordings from 2010-2016 was done. 604 children and young adults with T1D were recruited from five hospitals with pediatric diabetes clinics. 559 patients aged 2-35years with known date of birth were included. Clinical data on retinopathy and neuropathy were analyzed. There was no information on renal function/ nephropathy.<br />Most data were missing. There was documentation on HbA1C, plasma glucose and complications in less than half of the patient files. Of those with registered HbA1c values (42.2%), 36% had HbA1c&gt;12.5%. There was high prevalence of retinopathy (21.5%) and neuropathy (29.4%) in spite of short mean duration of diabetes (6.2±4.1years).<br />Many patients with T1D in Tanzania have poor metabolic control. Microvascular complications are common already after a short duration of diabetes, but the results have to be interpreted with great caution because of study limitations. Better pediatric diabetes care as well as increased awareness of diabetes is needed. Studies in resource-poor countries need careful planning, if possible with prospective design.<br />Many patients with T1D in Tanzania have poor metabolic control. Microvascular complications are common already after a short duration of diabetes, but the results have to be interpreted with great caution because of study limitations. Better pediatric diabetes care as well as increased awareness of diabetes is needed. Studies in resource-poor countries need careful planning, if possible with prospective design.Allograft rupture is a rare complication of renal transplantation. We present a case of renal allograft rupture which did not lead to nephrectomy. A young woman underwent renal transplantation. On day 5 of transplantation, the patient complained of sudden pain over the transplant site and severe hemorrhage. the immediate exploration, shows allograft rupture. The rupture of allograft was repaired. The patient recovered without any complications our study revealed that, repair and salvage of renal allograft were successful and nephrectomy is not mandatory in renal allograft rupture.Bladder cancer metastasis to the inguinal lymph nodes is a rare event. We report a case of a 73 years old male patient, known case of hypertension, diabetes, and bladder cancer. He was admitted to King Faisal Specialist Hospital (KFSHRC) in Riyadh, Saudi Arabia under urology department. He has a history of urinary retention and dialysis due to obstructive uropathy, right hydrocelectomy, multiple transurethral resection of bladder tumor (TURBT) chips, partial cystectomy, and right inguinal lymph node biopsy. Later on, he was found to have a urethral tumor, which was diagnosed by a biopsy, along with inguinal lymph nodes metastasis.A case is presented demonstrating improved efficacy of the use of oral methenamine hippurate and vitamin C urinary tract infection prophylaxis achieved by adding self-administered acetic acid irrigation twice daily during routine intermittent bladder self-catheterization in a post-menopausal female patient with multiple sclerosis. The patient in this case report is me, a retired radiologist.Hutch diverticulum is a rare congenital entity that develops in the ureteral hiatus or in its proximity and is accompanied by reflux in most cases. There are very few reported cases and most of them are in children and predominately at solitary side. Adult cases are rare. We review the literature and present a case of a 65-year-old man with bilateral hutch diverticulum asymptomatic revealed during assessment of hematuria.tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase (TRMU) deficiency causes an early onset potentially reversible acute liver failure, so far reported in less than 30 patients. We describe two new unrelated patients with an acute liver failure and a neuroimaging compatible with Leigh syndrome (LS) due to TRMU deficiency, a combination not previously reported. Our report enlarges the phenotypical spectrum of TRMU disease.Measurement of ambient aerosol and nitrogen dioxide (NO2) is important as they are major pollutants from the burning of fossil fuel and biomass. [https://www.selleckchem.com/ selleck products] In the present work, a differential photoacoustic spectrometer (D-PAS) was developed for simultaneous, online measurements of aerosol optical absorption and NO2 concentration. A novel photoacoustic resonator was designed and employed in the D-PAS for controlling a large flow rate, improving response time, and keeping the flow noise at a low level. The detection limits of 1.0 Mm-1 and 0.87 ppb for aerosol absorption and NO2 concentration measurements were achieved with a lock-in amplifier time constant of 1 s. The D-PAS accuracy was demonstrated by performing a long-time, continuous measurement of aerosol, and NO2 in ambient air. The measured results of NO2 are consistent with the NOx analyzer and environmental monitoring station results.