Influence of tricuspid vomiting upon success throughout individuals with heart amyloidosis

3 (SD,42.10) weeks and 39.3 (SD,35.11) respectively. Patients with malignant pathology who consumed more than 1.2g/kg/day of protein had increased hand-grip strength and preservation of FFM, while those who consumed 0.8g-1.2g/kg/day of protein had deteriorating hand grip strength and significant FFM reduction (p=0.004). Patients with benign pathology showed significant improvement in hand-grip strength (p<0.001) and increase in FFM (p<0.001) with higher protein intake.
Protein supplementation is paramount in nutrition recovery and muscle mass restoration among upper gastrointestinal surgical patients. Protein intake of at least 1.2g/kg/day was especially important among patients with malignancy to preserve muscle mass and strength.
Protein supplementation is paramount in nutrition recovery and muscle mass restoration among upper gastrointestinal surgical patients. Protein intake of at least 1.2 g/kg/day was especially important among patients with malignancy to preserve muscle mass and strength.
One of the essential parameters of athletes that enhancing fitness and success rate in sports career is body composition. Additionally, perfect performance of athletes is significantly influenced by training and dietary intake. This study aimed to determine the association between the dietary inflammatory index (DII) and body composition among Iran's Paralympic athletes with hemodialysis and hemophilia.
A cross-sectional study was conducted, which recruited 100 athletes with hemodialysis and hemophilia who participated in the 2020 competitive pre-season tests. Sociodemographic, anthropometric, physical activity, sleep pattern, and dietary intake were used in the analysis. DII was scored based on information obtained using food frequency questionnaire. Body composition was assessed using Bio impedance analyzer BIA (TANITA BC-418) and with 7-points skinfold measures. Linear regression model was used for finding the associations between DII with body composition.
The overall DII score was-2.83 and there was a significant difference for the mean body fat percent (P=0.001) and mean fat free mass percent (P=≤0.001) between 7-points skin fold measurements and BIA. No significant association had been found between the DII of the participants with the components of their body composition including, body mass index BMI (P=0.99), waist circumference (P=0.33), waist hip ratio (P=0.25), fat mass percent (P=0.47) and fat free mass percent (P=0.47).
Although athletes in the current study had DII scores indicating their anti-inflammatory diets, we did not find any significant associations between DII with the parameters of body composition.
Although athletes in the current study had DII scores indicating their anti-inflammatory diets, we did not find any significant associations between DII with the parameters of body composition.
The hydration status is a predictor of survival in critically ill patients. However, it is unclear whether this association depends on the patient clinical condition. This study was designed to analyze the impact of hydration status on survival of critically ill patients with acute kidney injury (AKI) with or without sepsis.
A prospective cohort study following critically ill patients with AKI consecutively admitted over a one-year period to a teaching hospital intensive care unit (ICU). All patients with AKI stage three or higher of the KDIGO score were included. The hydration status was evaluated through the overhydration (OH) parameter of spectroscopy bioimpedance and sepsis was defined according Sepse-3 criteria. The survival analysis used adjusted competing-risks regression.
Forty-eight patients were included, 27 (56%) with a sepsis diagnosis. The main negative predictors of survival among sepsis patients, adjusted by SAPS3 score, were higher OH (SHR 1.1, 95% CI 1.0-1.2, p=0.02), mechanical ventilation (SHR 6.9, 95% CI 1.0-47.8, p=0.04) and older age (SHR 1.1, 95% CI 1.0-1.1, p=0.005). The predictors in non-sepsis patients were lower OH (SHR 0.82, 95% CI 0.71-0.95, p=0.008) and mechanical ventilation (SHR 12, 95% CI 2.4-6.6, p<0.001).
This finding suggests that extracellular overhydration is an independent predictor of survival in critically ill patients with sepsis, but it seems to have opposite effect in non-sepsis patients.
This finding suggests that extracellular overhydration is an independent predictor of survival in critically ill patients with sepsis, but it seems to have opposite effect in non-sepsis patients.
The fat mass and obesity-associated (FTO) gene may influence the risk of breast cancer (BC). The single nucleotide polymorphisms (SNPs) of FTO gene may exert different impacts on different types of BC. In this study, we investigated the association between FTO SNP rs9939609 and the status of estrogen receptor (ER), progesterone receptor (PR), P53, and human epidermal growth factor receptor-2 (HER-2) in BC patients.
Our case-control study was included 540 Iranian participants aged 35 to 70 (180 women with BC as the case group and 360 healthy controls). After genotyping for risk allele rs9939609 of the FTO gene, a logistic regression was applied to elucidate the association between FTO SNP rs9939609 and BC risk based on the receptor status.
The number of HER-2 negative patients was significantly higher in FTO rs9939609 risk allele carrier group (61.5% vs. 41.4%, P<0.05). A significant association was found between BC and rs9939609 FTO gene polymorphism only in HER2 negative BC patients (OR=1.79, CI95% 1.2-3.56, P=0.03). No association was identified between FTO rs9939609 polymorphism and the status of ER, PR, and P53.
We indicated that FTO SNP rs9939609 can be a potential therapeutic target particularly in HER-2 negative BC cases. The importance of this risk allele in BC pathogenesis needs to be further highlighted.
We indicated that FTO SNP rs9939609 can be a potential therapeutic target particularly in HER-2 negative BC cases. The importance of this risk allele in BC pathogenesis needs to be further highlighted.
Women of reproductive age (WRA) are at increased risk for anemia and iron deficiency. However, there is limited population-level data in India, which could help inform evidence-based recommendations and policy.
To conduct a population-based biomarker survey of anemia, iron deficiency, and inflammation in WRA in Southern India.
Participants were WRA (15-40y) who were not pregnant or lactating. Blood samples (n=979) were collected and analyzed for hemoglobin (Hb), serum ferritin (SF), soluble transferrin receptor (sTfR), C-reactive protein (CRP), and alpha-1 acid glycoprotein (AGP). Anemia and severe anemia were defined as Hb<12.0 and<8.0g/dL. Serum ferritin was adjusted for inflammation using BRINDA methods. Iron deficiency was defined as SF<15.0μg/L, iron insufficiency was defined as SF<20.0 and<25.0μg/L, and iron deficiency anemia was defined as Hb<12.0g/dL and SF<15.0μg/L. Inflammation was defined as CRP > 5.0mg/L or AGP > 1.0g/L. Restricted cubic spline regression models were also used to determine if alternative SF thresholds should be used t to classify iron deficiency.
A total of 41.5% of WRA had anemia, and 3.0% had severe anemia. Findings from spline analyses suggested a SF cut-off of < 15.0μg/L, consistent with conventional cut-offs for iron deficiency. 46.3% of WRA had SF<15.0μg/L (BRINDA-adjusted 61.5%), 55.0% had SF<20.0μg/L (72.7%), 61.8% had SF<25.0μg/L (81.0%), and 30.0% had IDA (34.5%). 17.3% of WRA had CRP > 5.0mg/L and 22.2% had AGP > 1.0g/L. The prevalence of ID (rural vs. urban 49.1% vs. 34.9%; p=0.0004), iron insufficiency (57.8% vs. 43.8%; p=0.0005), and IDA (31.8% vs. read more 22.4%; p=0.01) were significantly higher in rural areas, although CRP levels were lower and there were no differences in elevated CRP or AGP.
The burden of anemia and iron deficiency in this population was substantial, and increased after adjusting for inflammation, suggesting potential to benefit from screening and interventions.
NCT04048330.
NCT04048330.
A large proportion of hospitalised COVID-19 patients are overweight. There is no consensus in the literature on how lean body mass (LBM) can best be estimated to adequately guide nutritional protein recommendations in hospitalised patients who are not at an ideal weight. We aim to explore which method best agrees with lean body mass as measured by bioelectric impedance (LBM
) in this population.
LBM was calculated by five commonly used methods for 150 hospitalised COVID-19 patients previously included in the BIAC-19 study; total body weight, regression to a BMI of 22.5, regression to BMI 27.5 when BMI>30, and the equations described by Gallagher and the ESPEN ICU guideline. Error-standard plots were used to assess agreement and bias compared to LBM
. The actual protein provided to ICU patients during their stay was compared to targets set using LBM
and LBM calculated by other methods.
All methods to calculate LBM suffered from overestimation, underestimation, fixed- and proportional bias and widenutritional protein.
The protocol of the BIAC-19 study, of which this is a post-hoc sub-analysis, is registered in the Netherlands Trial Register (number NL8562).
The protocol of the BIAC-19 study, of which this is a post-hoc sub-analysis, is registered in the Netherlands Trial Register (number NL8562).
Patients with neuroendocrine tumours (NET) are at nutritional risk due to symptoms and treatment side-effects. Current evidence-based guidelines lack information regarding optimal nutritional management. This study aimed to describe health professional knowledge and management of nutrition complications in GEP NET patients and summarise current international practice.
Multidisciplinary health professionals who regularly provide care for NET patients, were invited to participate in a 21-item online survey. Survey questions asked about symptom prevalence, nutrition screening, assessment practices, and vitamin deficiency screening and supplementation practices. General demographic information was recorded.
In total 73 health professionals completed the survey. Many worked in Australia (52%) and the United Kingdom (19%). Most responses were provided by medical oncologists (25%), nurses (23%) and dietitians (30%). Diarrhoea and fatigue were reported as the most common symptoms (86% and 60%, respectively) andn this at-risk patient group.
Retroperitoneal sarcoma (RPS) is a rare tumour that can reach exceptionally large size at diagnosis and affects body weight with its volume. We investigated the risk of nutritional status misclassification based on the Global Leadership Initiative on Malnutrition (GLIM) criteria in RPS patients.
We retrospectively analyzed the baseline data of patients with primary RPS including anthropometry, Malnutrition Universal Screening Tool (MUST) score and skeletal muscle index (SMI) calculated on preoperative CT scan. Phenotypic GLIM criteria considered were non-volitional weight loss, low-BMI and low muscle mass. MUST score, being inclusive of weight loss, was chosen as its surrogate. Reduced muscle mass was defined with SMI cut-offs <38.5-52.4cm
/m
for female and male respectively.
From 2018 to 2020, 100 consecutive patients (male/female 48/52) were included. Median age was 61 (48-68) years, median BMI 24.6 (21.5-27.4) kg/m
. Seven patients (7%) reported MUST score ≥2 and 80 (80%) score 0. Five patients (5%) were underweight, 44 (44%) overweight and obese.