Qualityoflife benefits right after pelvic exenteration for main arschfick cancer malignancy
In our study we aimed to analyze sleep variability and activity in patients with cystic fibrosis (CF) during their hospital stay.
Forty-three CF patients were recruited and have been divided into two subgroups exacerbated (n=18) and non-exacerbated (n=25). During the course of their hospital stay we used VitaLog, a minimal-impact biomotion device, in order to determine total sleep time (TST), time in bed (TIB), sleep efficiency (SE) and intra patient standard deviation (IPSD) of TST.
TST was 5.1h±1.5h and ranged from 0.6h to 7.9h.TIB was 17.7h±3.8h and ranged from 5.6h to 23.9h. SE was 70.0%±17.0% and ranged from 13.6% to 98.5%. TST was higher in non-exacerbated patients (5.3h±1.4h vs. 4.8h±1.6h, p=0.008) whereas TIB was lower in non-exacerbated patients (17.0h±3.7h vs. 18.5h±3.8h, p=0.002). We also found that SE was better in non-exacerbated patients (73.1%±14.6% vs. 66.6%±18.8%, p=0.002). Furthermore, we observed that IPSD of TST was higher in exacerbated patients (1.3h±0.5h vs. 0.9h±0.4h, p=0.004).
In general, in CF patients TST was short and SE poor during the night. Furthermore, in the course of their hospital stay patients showed low activity. In exacerbated patients sleep quality was lower compared to non-exacerbated patients.
In general, in CF patients TST was short and SE poor during the night. Furthermore, in the course of their hospital stay patients showed low activity. In exacerbated patients sleep quality was lower compared to non-exacerbated patients.
Solid fuel use for cooking is a main source of household air pollution, particularly in rural China. Evidence on the association between household air pollution and sleep quality remains limited. This study aimed to examine the association between household solid fuels used for cooking and sleep disturbance.
The data of 283,170 adults from baseline survey of the China Kadoorie Biobank Study were included. Detailed information about exposure to solid fuels used for cooking were collected. Sleep disturbance was indicated as any of the three sleep disorders, including disorders of initiating and maintaining sleep, disorders of early morning awakening, and daytime dysfunction. Logistic regression analysis was used to examine the association between sleep disturbance and level of exposure to household solid fuels used for cooking.
About 18% of participants reported sleep disturbance. Fully adjusted analysis indicated exposure to household solid fuels used for cooking was significantly associated with sleep disturbance. Compared to those with 0-3 years exposure (first tertile) to solid fuels used for cooking, the participants with 3-26 years exposure (second tertile) and >26 years exposure (third tertile) had greater odds of having sleep disturbance at 1.16 (95% CI 1.12-1.19) and 1.33 (95% CI 1.29-1.37) times, respectively.
Use of household solid fuels is associated with prevalence of sleep disturbance; the longer duration of exposure to solid fuels use for cooking, the higher is the prevalence of sleep disturbance. Further study is warranted to examine the underlying mechanisms of the association.
Use of household solid fuels is associated with prevalence of sleep disturbance; the longer duration of exposure to solid fuels use for cooking, the higher is the prevalence of sleep disturbance. Further study is warranted to examine the underlying mechanisms of the association.An integrated two-phase AD with acidogenic off-gas diversion from a leach bed reactor to an upflow anaerobic sludge blanket was developed for improving methane production. However, this system had its own technical limitation such as mass transfer efficiency for solid-state treatment. In order to optimize the mass transfer in this two phase AD system, leachate recirculation with various water replacement rates regulating the total solids contents (TS) at 12.5%, 15%, and 17.5% was aim to investigate its effect on methane generation. The solubilization of food waste was increased with decreasing TS content, while the enzymatic hydrolysis showed the opposite trend. A TS contents of 15% presented the best acidogenic performance with the highest hydrogen yield of 30.3 L H2/kg VSadded, which subsequently resulted in the highest methane production. The present study provides an easy approach to enhance food waste degradation in acidogenic phase and energy conversion in methanogenic phase simultaneously.A simple cluster-ligand interaction model is introduced to describe the surface passivation of bimetallic gold clusters by SUP (Thioureidopeptide) and SeUP (Selenoureidopeptide) ligands. AU-15330 nmr The conformational search based on neutral peptide binding modes and their computed interaction energies show the existence of various structural isomers within 10 kcal mol-1. Further, the negatively charged deprotonated peptide was found to strongly interact with metal cluster through the carboxylate unit. Irrespective of the mode of binding and configuration the metal cluster found to exist in parent geometry in all three charge states. The calculated HOMO-LUMO gap of ligated clusters predicts an increase in chemical stability after the ligation. Moreover, the ligation was found to decrease the energy required for oxidation and reduction. The excited-state calculations indicate absorption maxima at 200-400 nm corresponds to the LMCT transition. In all the hybrid cluster models the donor and acceptor end of the peptide were found to remain intact. However, the charge migration dynamics observed only in the homo-metallic gold-ligand hybrids, owing to the larger charge separation.
The 2008 Recession was a global event that led to funding cuts for programs and services in the United States; though this recession officially ended in 2009, its aftershocks continued through 2012. We evaluated the relationship between the severity of the Great Recession's aftermath and spatial access to combined prevention services (i.e. HIV testing, syringe service programs, substance use disorder treatment program) for people who inject drugs (PWID) living in 19 metropolitan statistical areas (MSAs) in the United States.
The unit of analysis was the ZIP code; we sampled ZIP codes in these 19 MSAs where ≥1 PWID lived in 2009 and 2012, according to the CDC's National HIV Behavioral Surveillance. We used administrative data to describe the combined prevention environment (i.e., spatial access to HIV testing) for each ZIP code, and measured the severity of the recession's aftermath in each ZIP code, and in the counties and MSAs where these ZIP codes were located. Multilevel modeling estimated associations between changes in the aftermath of the Great Recession and ZIP code-level changes in spatial access to combined prevention services from 2009 to 2012.